Clotting pathways

Hi guys, We are back in Business.. and with a bang.. We have recently launched outr YOuTUbe channel.. PhysiologyOPen

We are going to post atleast one post per week from now onwards.

Ask any queries on Physiology.. And 

Watch clotting pathways at my channel on youtube:

Visit the channel for more details:  PhysiologyOpen on Youtube

Blood groups

1. Define Landsteiner’s law
2. List the uses of blood grouping
3. Who is universal donor & universal acceptor. Are these concepts relevant today?
4. List the hazards of mismatched blood transfusion{Transfusion reactions}
5. What are the indications, precautions of blood transfusion?
6. Name few systems of blood grouping.
7. What is the basis of ABO blood grouping & Rh typing?
8. What is major, minor cross matching?
9. What is Erythobalstosis fetalis

WBC and immunity

1. Classify WBC’s. With the help of a table describe the features of each.
2. What is immunity ? 
3. Classify immunity and briefly explain innate and acquired immunity
4. What is the difference between acquired & innate immunity
5. Briefly explain phagocytosis.
6. Explain the role of following cells in immune response: Neutophil, Eosinophil, Basophil, Monocyte, Macrophage, T lymphocytes, B lymphocyte, NK cells
7. Define leukemia & leukamoid reaction 
8. Name the causes of leucopenia, leucocytosis.
9. What is Arneth index?
10. What is Reticulo-endothelial system (Mononuclear macrophage system)? What are its functions?
11. What is Passive immunity (natural & artificial)?
12. What is Active immunity (natural & artificial)?
13. Describe the functions of antibodies.
14. Name the different types of T cell
15. What are T Helper cells?
16. What is Complement system? What are its functions?
17. Name the types of Immune disorders.
18. What is MHC Complex?
19. Explain cell mediated immunity. List the various cells involved in it.
20. Explain humoral immunity, List the functions of antibodies.
21. Name the WBCs responsible for killing intracellular & extracellular organism 

Platelets

Must must know

What are the 3 events the lead to complete stoppage of bleeding after injury?

What is normal platelet count? When it is called as thrombocytopenia?

What are the causes of thrombocytopenia ?  

Give 4 functions of platelets or What are the functions of platelets ?

Briefly explain the role of platelets in homeostasis.

What is the difference between primary & secondary hemostasis?

What should be the next step you will take in a dengue patient when platelet count

goes below 20,000? Justify your answer.

Platelets buds from ____________cyte.

Define bleeding time? Name two methods used to determine bleeding time? What is its

significance? Give its normal value?

Nice to know ( physiological basis of use of certain drugs)

Name  one drug which is ADP receptor antagonist? When will you advice it?

Name one one drug which is gpIIb/IIIa antagonist? What are its uses

Anemia

What are blood or hematological indices? How are they calculated ?

Classify anemia based on hematological indices (blood indices i.e MCH, MCV, MCHC)

Classify anemia based on etiology

Briefly explain iron deficiency anemia

Briefly explain Vit B12 and folic acid deficiency anemia

Erythrocytes

What are the functions of hemoglobin/

What are the functions of RBC

What is polycythemia? What are its physiological and pathological causes

Must must know

Stages and regulation of erythropoiesis

Types of jaundice

Must know

What is plasma?

What is the difference between plasma & serum?

What is packed cell volume (PCV)?

What is hematocrit?

Name important plasma proteins. Give their normal value.

Give normal value of albumin:globulin ratio. What is its significance?

What are the functions of plasma proteins?

Plasma protein contributing maximum to osmotic pressure is ____________ . Give reason for your answer.

For equal amount fibrinogen contributes more to viscosity as compared to albumin.

Justify this statement.